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Does hematochezia need not do colonoscopy?

Author：Dr.Sunny Kim

Some people accidentally discover they have blood in their stool when they pass a medical examination or defecate. Because hematochezia or fecal occult blood positive cannot explain the occurrence that has bowel cancer certainly, further colonoscopy is needed to confirm the diagnosis. But in many cases patients have concerns about doing invasive colonoscopy and miss the best time for early diagnosis. 

Today, I would like to introduce a non-invasive colorectal cancer gene detection method, which is conducive to the early screening of colorectal cancer.

1.  What is colorectal cancer?

Colorectal cancer is also called colonic cancer. Most colorectal cancers develop from adenomatous polyps, but it takes about 10 years for adenomatous polyps to develop into advanced cancer.

2.  What are the risk factors for colorectal cancer?

a.    Age≥50

b.    A family history of colorectal cancer

c.    A history of inflammatory bowel disease, such as Crohn's disease or ulcerative colitis

d.    A history of polyps

e.    Unhealthy lifestyles and eating habits: Smoking, sedentary behavior,etc

3.  How to reduce the mortality rate of colorectal cancer?

Since most people have no obvious symptoms at the early stage, and it takes a long time for adenomatous polyps to develop into cancer, early screening is conducive to the early detection, diagnosis and treatment of colorectal diseases, which is the key to prevent the occurrence of colorectal cancer and reduce its mortality.

4.  What is the principle of noninvasive colorectal cancer gene detection?

Colorectal cancer generally occurs in the colorectal epithelium and starts to grow into the lumen of the intestine. During the process of its growth, tumor cells continuously shed into the intestinal lumen and are excreted with feces, which contains abnormal proliferative cells and cell components shed from the surface of these intestinal tumors. The non-invasive bowel cancer gene test detects mutations in specific genes in the stool to determine whether the bowel is cancerous or precancerous.

5.  What are the advantages of the test?

a.    The accuracy of the results was high

b.    It's completely noninvasive and requires only a small amount of stool

c.    No intestinal preparation is required and can be completed at home

d.    The detection scope covers the whole colorectum, without blind area

6.  Who are the applicable people for the test?

a.    Healthy people over the age of 45

b.    People with positive occult blood

c.    People with digestive tract symptoms or changes in bowel habits (diarrhea, abdominal pain, abdominal distension, hematochezia, constipation)

d.    People with a family history of colorectal cancer and poor diet and lifestyle habits

e.    People who need postoperative review for colorectal cancer

f.     People with anorectal benign diseases (such as hemorrhoids, anal fistula, anal fissure, perianal mass, etc.)

g.    People at high risk who are unwilling or unable to undergo colonoscopy for various reasons

7.  Several situations of interpretation of the test results

a.    If the test result is negative, it means no genetic variation has been detected. It is recommended to repeat the test every 1-3 years.

b.    If the test result is positive, it indicates that genetic variation has been detected, and further colonoscopy is recommended to make a definitive diagnosis.

c.    If the examination result is gray area, it indicates that mild genetic variation has been detected, and further colonoscopy is suggested to make a definitive diagnosis.

8.  What are the precautions before the test?

a.    If you are taking berberine, it is recommended that you stop taking berberine for one week before the test. If you are taking antibiotics, you are advised to stop taking them for at least one day before the test.

b.    Watery stools carry few exfoliated cells，it is recommended to do the test after the stool is formed.

c.    Stool samples should be collected using a matching collection device.

d.    Do not mix urine with feces, so as not to cause dilution of feces and affect the detection.

PRICE：

Special price: RMB 998 

Date: valid to Sep 30th

The original price will be restored to RMB 1998 from October 1st.

HOTLINE:

10-64651561/2/3

Due to the low sensitivity and high false positive rate of the current preliminary screening test (such as fecal occult blood), the detection rate of lesions found in colonoscopy is low. Moreover, colonoscopy requires a large amount of manpower and material resources, which also wastes medical resources to a certain extent. Due to the complex intestinal preparation, the examination process of colonoscopy is more painful, and many patients have poor compliance, making regular review difficult.

On the one hand, non-invasive colorectal cancer gene test can provide colonoscopy doctors with more patients with therapeutic value, and if the gene test result is positive, informing the doctor about the result can get more attention from them, and the quality of colonoscopy will also be greatly improved for patients.

Therefore, as an accurate, convenient and non-invasive screening technology, non-invasive colorectal cancer gene detection will help to improve the screening level of colorectal cancer and improve the early diagnosis and treatment rate of colorectal cancer