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Reading the Science of Your Gut


There is a saying, "you are what you eat". In fact, it's not only what you eat, but also what your gut is sensitive to and what can be absorbed, determine what kind of people you are and what kind of quality of life you have.

Human gut is a complex and dynamic ecological environment, which contains a large number of microorganisms. There are at least 1000 kinds of microorganisms living in the human intestine, with a number of up to 10 trillion, which is equivalent to the total number of our body cells. The total number of genes of intestinal microorganisms is 100 times of the human genome. The active metabolism of microorganisms in human intestinal flora is considered as the "second genome" acquired by human body.
Diverse and complex intestinal flora, to some extent, shows your health. It was found that obesity, insulin resistance and inflammation were closely related to intestinal microbial diversity.


Some factors, such as the structure and habits of diet, or cardiovascular diseases (such as atherosclerosis, hypertension), type II diabetes, colorectal cancer, mental / neurological diseases (such as autism, anxiety, depression, Alzheimer's, Parkinson's) and other diseases, will change the intestinal flora accordingly.


But if you blindly supplement yourself with probiotics that are not suitable for you, your immunity may get worse! After all, there are many kinds of probiotics on the market, and different strains may have different functions, and just like there are no two identical leaves in the world, everyone's intestinal flora is also different.

 

Therefore, through the detection of intestinal flora, timely monitoring of the abnormalities of related flora can indicate the risk of disease. It is an effective way to prevent the occurrence of related diseases and relieve the symptoms with improve the intestinal microecology and targeted intervention and conditioning.

 

A new detection technology has been developed and promoted.

It is to extract the total bacterial DNA from fecal samples, then analyze and compare it, so as to describe the intestinal microecological structure and diversity of the client, especially the content and structure ratio of the intestinal functional core flora, monitor the probiotics, conditional pathogens and some food borne pathogens in the gut, predict the risk of related diseases, and provide targeted personalized health management suggestions for the client.

 

It should be noted that, the occurrence and development of most diseases are complex, which is the result of the joint action of living habits, genetic factors and environmental factors. Disease risk tips cannot replace clinical medical testing. If the client has certain disease characteristics or discomfort symptoms, it is recommended to see a doctor in time and receive further testing and treatment under the guidance of a clinician.

Sources: 

[1] Miquel S. Faecalibacterium prausnitzii and human intestinal health [J]. Curr Opin Microbiol, 2013 Jun,16(3):255-61.

[2] Wollowski I. Protective role of probiotics and prebiotics in colon cancer [J]. Am J Clin Nutr, 2001 Feb,73(2 Suppl):451S-455S.

[3] Brady LJ. The role of probiotic cultures in the prevention of colon cancer [J]. J Nutr, 2000 Feb,130(2S Suppl):410S-414S.

[4] Nakayama Y. Oral administration of Lactobacillus gasseri SBT2055 is effective for preventing influenza in mice [J]. Sci Rep, 2014 Apr 10,4:4638.

[5] Perrin Y, Nutten S. Comparison of two oral probiotic preparations in a randomized crossover trial highlights a potentially beneficialeffect of Lactobacillus paracasei NCC2461 in patients with allergic rhinitis [J]. Clin Transl Allergy, 2014 Jan 6,4(1):1.

[6] Zhang J , Guo Z , Xue Z , et al. A phylo-functional core of gut microbiota in healthy young Chinese cohorts acrossifestyles, geography and ethnicities[J]. ISME Journal: Multidisciplinary Journal of Microbial Ecology, 2015, 9(9):1979-1990.

[7] Ishfaq A , Badal R , Salman K , et al. Microbiome, Metabolome and Inflammatory Bowel Disease[J]. Microorganisms, 2016, 4(2):20.

[8] Duvallet C , Gibbons S M , Gurry T , et al. Meta-analysis of gut microbiome studies identifies disease-specific and shared responses[J]. Nature Communications, 2017, 8(1):1784.

[9] Parracho H M, Bingham M O, Gibson G R, et al. Differences between the gut microflora of children with autistic spectrum disorders and that of healthy children.[J]. Journal of Medical Microbiology, 2005, 54(10):987-91.

[10] Krajmalnikbrown R , Lozupone C , Kang D W , et al. Gut bacteria in children with autism spectrum disorders: challenges and promise of studying how a complex community influences a complex disease.[J]. Microb Ecol Health Dis, 2015, 26:26914.

[11] Kazemi A , Noorbala A A , Azam K , et al. Effect of probiotic and prebiotic vs placebo on psychological outcomes in patients with major depressive disorder: A randomized clinical trial[J]. Clinical Nutrition, 2018:S0261561418301614.

[12] Kanji S , Fonseka T M , Marshe V S , et al. The microbiome-gut-brain axis: implications for schizophrenia and antipsychotic induced weight gain[J]. European Archives of Psychiatry and Clinical Neuroscience, 2017.

[13] Mancuso C , Santangelo R . Alzheimer’s disease and gut microbiota modifications: The long way between preclinical studies and clinical evidence[J]. Pharmacological Research, 2017:S1043661817315748.

[14] Cattaneo A , Cattane N , Galluzzi S , et al. Association of brain amyloidosis with pro-inflammatory gut bacterial taxa and peripheral inflammation markers in cognitively impaired elderly[J]. Neurobiology of Aging, 2017, 49:60-68.

[15] Otsuka M, Ichiya Y, Hosokawa S, et al. Striatal blood flow, glucose metabolism and 18F-dopa uptake: difference in Parkinson's disease and atypical parkinsonism.[J]. J Neurol Neurosurg Psychiatry, 1991, 54(10):898-904.

[16] Hill-Burns E M, Debelius J W, Morton J T, et al. Parkinson's disease and Parkinson's disease medications have distinct signatures of the gut microbiome[J]. Movement Disorders, 2017, 32(5):739.[17]

[17] Wan Z , Hu L , Hu M , et al. Helicobacter pylori infection and prevalence of high blood pressure among Chinese adults[J]. Journal of Human Hypertension, 2017.

[18] Wan Z , Hu L , Hu M , et al. Helicobacter pylori infection and prevalence of high blood pressure among Chinese adults[J]. Journal of Human Hypertension, 2017.GZ001VL0NSRC25M- 23

[19] Higashi K, Shige H, Ito T, et al. Effect of a low-fat diet enriched with oleic acid on postprandial lipemia in patients with type 2 diabetes mellitus[J]. Lipids, 2001, 36(1):1-6.

[20] Boleij A , Tjalsma H . Gut bacteria in health and disease: a survey on the interface between intestinal microbiology and colorectal cancer[J]. Biological Reviews, 2012, 87(3):0-0.

[21] Ray, Katrina. Gut microbiota: Colorectal cancer—driven by inflammation and gut bacteria?[J]. Nature Reviews Gastroenterology & Hepatology, 2012, 9(10):558-558.

[22]欧阳军.自闭症儿童的饮食治疗[J].东方食疗与保健, 2004(11):48-49.

[23]陈飞.焦虑症最基本的饮食建议[J].现代养生(下半月版), 2017(10).

[24]李皖生.这些饮食习惯有助于预防阿尔茨海默症[J].科学养生, 2017(2):37-38.

[25]刘宋云,熊念,王涛.与帕金森病预防和治疗相关的饮食研究[J].中华神经科杂志, 2013, 46(10):663-666.

[26]胡晓娟,王奡掰.抗动脉粥样硬化的健康饮食指导[J].中国民康医学, 2012, 24(3).

[27]乌日丽其,宋华,李左军,等.结直肠癌患病饮食相关危险因素病例对照研究[J].疾病监测与控制, 2016, 10(1):70-72